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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10230 | MC-4R Agonist 1 | Others | |
MC-4R Agonist 1 is an agonist of human melanocortin-4 receptor (MC-4R) and can be used in the research of sexual dysfunction, obesity, and diabetes. | |||
T25310 | Dersimelagon | MT-7117 | Melanocortin Receptor |
Dersimelagon (MT-7117) is an orally active, selective agonist for the melanocortin 1 receptor (MC1R), demonstrating EC50 values of 8.16 nM (h), 3.91 nM (cm), 1.14 nM (m), and 0.251 nM (r) across species such as human, cy... | |||
T12415 | PF-00446687 | Others | |
PF-00446687 is a selective agonist of melanocortin-4 receptor (MC4R) (EC50 of 12 ± 1 nM). | |||
T79091 | Bivamelagon hydrochloride | MC-4R Agonist 2 hydrochloride | Melanocortin Receptor |
MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction. [1] | |||
TP2154 | RO27-3225 TFA (274682-89-2 free base) | RO27-3225 TFA | Others |
RO27-3225 TFA is a potent and selective agonist of melanocortin 4 receptor (MC4R; EC50: 1 nM and 8 nM for MC4R and MC1R) with neuroprotective and anti-inflammatory effects. RO27-3225 TFA shows ~30-fold selectivity for MC... | |||
T79090 | Bivamelagon | MC-4R Agonist 2 | Melanocortin Receptor |
MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and erectile dysfunction [1]. | |||
T76301 | Agouti-related Protein (AGRP) (83-132) Amide (human) | ||
Agouti-related Protein (AGRP) (83-132) Amide (human) is a segment derived from the agouti-related protein (AGRP), abundantly present in the hypothalamus' arcuate nucleus. It predominantly functions as an inverse agonist ... | |||
T71559 | Melanotan II acetate | ||
Melanotan II acetate is an agonist of melanocortin receptor 1 (MC1R), MC3R, MC4R, and MC5R. It has been shown to improve recovery of sciatic nerve function after mechanical injury and increase cisplatin-induced decreases... | |||
T35406 | α-MSH TFA | ||
α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocyt... |